Riva Tuner Statistics fixed my frame pacing issues lossless scaling in PoE 2
Currently had a lot of Micro stutters every 6-7 seconds in PoE2.
I used the ingame frame rate lock and it was horrible.
Riva tuners framerate limit kinda magically made the frame pacing so much more stable it is weird and i can't explain it but it works.
If you have microstutters a lot even while going for example
144 hz display -> fps set to 48 ingame -> LSFG 3.0 x3 -> DXGI
Try disable VSYNC ingame and the fps limit ingame and use VSYNC over the Lossless scaling window and limit your frames with Riva Tuner.
Tell me if it helped !
EDIT
if you have micro stutters ingame try to disable the "G-Sync support" under Render Options
Also try the default sync mode vs the Vsync mode